© 2019 by Arctic Pharma AS.

November 2018
Klaveness, J.; Sieng, B.; Lundvall, S.; Bøen, C. A.; Hnida, K. LDHA Activity Inhibitors. PCT Int. Appl. WO/2018/211277, 2018.

Abstract: The invention provides compounds of formula (I), stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof: (I) wherein A1 to A6 and R1 to R4 are as defined herein. Such compounds are suitable for use in the treatment or prevention of diseases or conditions which are mediated by the activation of lactate dehydrogenase A (LDHA), for example cancer.

Klaveness, J.; Sieng, B.; Lundvall, S.; Bøen, C. A.; Hnida, K. LDHA Activity Inhibitors. PCT Int. Appl. WO/2018/211278, 2018.

Abstract: The invention provides compounds of formula (I), stereoisomers and pharmaceutically acceptable salts thereof: (I) wherein A1 to A4, R1 and RP are as defined herein. Such compounds are suitable for use in the treatment or prevention of diseases or conditions which are mediated by the activation of lactate dehydrogenase A (LDHA), for example cancer.

November 2018
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